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Learn more about the history of Tasigna® and the alleged failures of its parent company Novartis®
Tasigna® (nilotinib) is a prescription drug that is often prescribed to treat chronic myeloid leukemia (CML).
Accounting for about 15% of all adult leukemia cases, CML is a type of cancer that begins deep in the bone marrow and travels throughout the bloodstream.
Tasigna® is a relatively new drug that was developed by Novartis® and approved for use in the treatment of CML in 2007–it works by blocking certain proteins that cause leukemia cancer cells to grow.
Tasigna® has become a very profitable drug for Novartis® since its original release–however, shortly after its first release, Tasigna® was associated with adverse incident reports indicating that the drug could be the cause of serious cardiovascular problems in some patients.
In 2011, the results of several studies reported that the use of Tasigna® was causing some patients to develop accelerated atherosclerosis–a condition in which the arteries delivering blood from the heart become hardened and narrow.
Typically, atherosclerosis develops gradually over time as a person ages–however, certain patients using Tasigna® began developing atherosclerosis within a few months.
Atherosclerosis can be very dangerous as it can result in serious cardiac and vascular events such as heart attack, or peripheral arterial disease.
In Canada, Novartis® amended its prescribing information to include a warning that Tasigna® can cause rapidly evolving vascular disease in some patients–however, Novartis® allegedly deliberately elected to preclude this critical warning from Tasigna® prescribing information in the United States.
In fact, the U.S. drug label for Tasigna® still does not contain any information about the risk of atherosclerosis.
Under certain circumstances, victims who suffer from unmarked Tasigna® side effects can pursue compensation for their losses.
Learn about Tasigna®-induced atherosclerosis and the potential for claiming compensation
Additional research efforts suggest a strong chance that Tasigna® is linked to atherosclerotic-related events, including stroke and heart attack.
While many patients taking Tasigna® are at a higher risk for atherosclerosis, the connection in many cases will be obvious because the medical literature describes an association between Tasigna® and a rare form of accelerated atherosclerosis.
According to the research concerning Tasigna®-induced atherosclerosis:
- Atherosclerosis generally develops over an extended time, taking years to become an acute risk.
- Rapid progression or sudden aggravation of atherosclerosis is uncommon.
- Tasigna®-induced atherosclerosis often develops much more quickly, giving doctors less time to diagnose and combat the condition.
A growing population of patients who have developed rapid atherosclerosis from using Tasigna® and suffered serious injuries has filed lawsuits against Novartis®.
The lawsuits allege that Novartis® allegedly knew as early as 2010 that Tasigna® could potentially cause accelerated atherosclerosis and/or other related conditions.
Novartis® allegedly knowingly and intentionally failed to warn about these risks in the U.S. in order to protect its financial interests.
August 2021 Update: On August 12, 2021, the United States Judicial Panel on Multidistrict Litigation ordered the creation of a Tasigna® class action lawsuit for claims involving this therapy.
December 2021 Update: A new study published this fall in the journal of Cardiology-Oncology identified a clear link between the use of Tasigna® and vasospastic angina–this is yet another potentially dangerous side-effect linked to the low blood flow problems caused by Tasigna®.
The Shield Justice Online team encourages those suffering after taking Tasigna® to request a free, private case evaluation for justice and compensation!
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